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A headache that arrives as the weather changes can make the connection feel obvious. For some people with migraine, weather is a possible trigger. But the timing alone does not establish the cause of a headache, fatigue or a sleepless night. The useful response is to look for a pattern, keep ordinary routines manageable and avoid explaining persistent or unusual symptoms away as “just the weather.” An approaching shelf cloud and rain shaft. Photo: NOAA National Severe Storms Laboratory, image nssl0389 , CC BY 2.0 as recorded on the file page. Commons thumbnail; no crop. The photograph illustrates weather, not a diagnosis. Weather may be a migraine trigger Mayo Clinic’s guidance says some people with migraine appear sensitive to weather changes. Possible triggers include bright sunlight, extreme temperatures, humidity and barometric-pressure changes. This does not mean that all headaches are migraines or that everyone reacts in the same way. A weather change may occur alongside o...